330 research outputs found

    Security and Privacy on Generative Data in AIGC: A Survey

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    The advent of artificial intelligence-generated content (AIGC) represents a pivotal moment in the evolution of information technology. With AIGC, it can be effortless to generate high-quality data that is challenging for the public to distinguish. Nevertheless, the proliferation of generative data across cyberspace brings security and privacy issues, including privacy leakages of individuals and media forgery for fraudulent purposes. Consequently, both academia and industry begin to emphasize the trustworthiness of generative data, successively providing a series of countermeasures for security and privacy. In this survey, we systematically review the security and privacy on generative data in AIGC, particularly for the first time analyzing them from the perspective of information security properties. Specifically, we reveal the successful experiences of state-of-the-art countermeasures in terms of the foundational properties of privacy, controllability, authenticity, and compliance, respectively. Finally, we summarize the open challenges and potential exploration directions from each of theses properties

    Characterization of the Small RNA Transcriptomes of Androgen Dependent and Independent Prostate Cancer Cell Line by Deep Sequencing

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    Given the important roles of miRNA in post-transcriptional regulation and its implications for cancer, characterization of miRNA facilitates us to uncover molecular mechanisms underlying the progression of androgen-independent prostate cancer (PCa). The emergence of next-generation sequencing technologies has dramatically changed the speed of all aspects of sequencing in a rapid and cost-effective fashion, which can permit an unbiased, quantitive and in-depth investigation of small RNA transcriptome. In this study, we used high-throughput Illumina sequencing to comprehensively represent the full complement of individual small RNA and to characterize miRNA expression profiles in both the androgen dependent and independent Pca cell line. At least 83 miRNAs are significantly differentially expressed, of which 41 are up-regulated and 42 are down-regulated, indicating these miRNAs may be involved in the transition of LNCaP to an androgen-independent phenotype. In addition, we have identified 43 novel miRNAs from the androgen dependent and independent PCa library and 3 of them are specific to the androgen-independent PCa. Function annotation of target genes indicated that most of these differentially expressed miRNAs tend to target genes involved in signal transduction and cell communication, epically the MAPK signaling pathway. The small RNA transcriptomes obtained in this study provide considerable insights into a better understanding of the expression and function of small RNAs in the development of androgen-independent prostate cancer

    A missing link in the estuarine nitrogen cycle?: coupled nitrification-denitrification mediated by suspended particulate matter

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    In estuarine and coastal ecosystems, the majority of previous studies have considered coupled nitrification-denitrification (CND) processes to be exclusively sediment based, with little focus onsuspended particulate matter (SPM) in the water column. Here, we present evidence of CND processes in the water column of Hangzhou Bay, one of the largest macrotidal embayments in the world

    Aerosols Monitored by Satellite Remote Sensing

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    Aerosols, small particles suspended in the atmosphere, affect the air quality and climate change. Their distributions can be monitored by satellite remote sensing. Many images of aerosol properties are available from websites as the by-products of the atmospheric correction of the satellite data. Their qualities depend on the accuracy of the atmospheric correction algorithms. The approaches of the atmospheric correction for land and ocean are different due to the large difference of the ground reflectance between land and ocean. A unified atmospheric correction (UAC) approach is developed to improve the accuracy of aerosol products over land, similar to those over ocean. This approach is developed to estimate the aerosol scattering reflectance from satellite data based on a lookup table (LUT) of in situ measured ground reflectance. The results show that the aerosol scattering reflectance can be completely separated from the satellite measured radiance over turbid waters and lands. The accuracy is validated with the mean relative errors of 22.1%. The vertical structures of the aerosols provide a new insight into the role of aerosols in regulating Earth\u27s weather, climate, and air quality

    Effect of Yeast Fermentation on Volatile Flavor Substances and Nutritional Properties of Rice Bran

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    To investigate the effect of yeast fermentation on the flavor as well as nutritional properties of rice bran. In this study, volatile flavor substances of rice bran at different fermentation periods (0, 12, 18, 24 and 30 h) were identified by headspace solid-phase microextraction-gas chromatography-mass spectrometry, key volatile substances affecting the flavor of rice bran before and after fermentation were determined by orthogonal partial least squares analysis, and finally a comprehensive sensory evaluation of fermented rice bran was carried out and the changes of its nutritional composition by the optimal time of fermentation were compared. The results showed that the content and types of volatile substances of rice bran changed significantly during the fermentation process, the content of aldehydes in unfermented rice bran accounted for 35.99% and the content of alcohols accounted for 14.21%, and the content of aldehydes decreased to 5.52% and the content of alcohols increased to 60.87% at 30 h of fermentation. Among them, there were 15 key volatile substances. In the sensory evaluation, there was a significant (P<0.05, P<0.01) correlation between key volatile substances and rice bran aroma, and the sensory score of rice bran improved after fermentation, and the best sensory score was obtained for rice bran fermented for 18 h. Nonanal and ethyl nonanoate had the most significant (P<0.01) effects on the overall score of rice bran. In terms of nutritional composition, the protein content of yeast fermented rice bran flour was improved by 38.41% and the fiber content was improved by 18.21%. It indicated that yeast fermentation could not only effectively improve the flavor of rice bran, but also enhance the nutritional properties of rice bran flour as a food ingredient

    Transcriptome analysis of Immune Response against Streptococcus agalactiae infection in the Nile Tilapia GIFT Strain

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    Streptococcus agalactiae (group B streptococcus, GBS), a broad-spectrum pathogen, causes great economic losses in fish aquaculture, especially the industry of tilapia. Until now, the knowledge of the immune response mechanism against S. agalactiae infection in tilapia has been limited. In the present study, the gill transcriptome of the tilapia from the GBS and the phosphate buffered saline (PBS) groups were sequenced. The transcriptomic analysis results presented the differentially expressed genes (DEGs) at different time points (DEGs number, 6 h: 2122, 9 h: 1851, 15 h: 1791, and 18 h: 2395) after GBS injection, and significantly enriched immune-related gene ontology (GO) terms such as the innate immune response. The significantly enriched immune pathways included the Toll-like receptor signaling pathway, the nucleotide oligomerization domain (NOD)-like receptor signaling pathway, the cytosolic-DNA sensing pathway, and the intestinal immune network for Immunoglobulin A (IgA) production. Most of the DEGs in Toll-like receptor signaling, NOD-like receptor signaling, and cytosolic-DNA sensing pathways presented upregulations at 18 h, which indicated that the innate immune pathways were activated. Two immune-related pathways (phagosome and cell adhesion molecules) were significantly enriched at all time points, suggesting that these two pathways might also play important roles in the immune response against the GBS infection. The results of HE staining showed that the gills of tilapia were damaged seriously at 9 h post-infection, which might be due to the possibility of pyroptosis resulting from the changes of DEGs in the NODlike receptor signaling pathway. This study provided new insight into the mechanisms of gill damage in fish infected with S. agalactiae.info:eu-repo/semantics/publishedVersio

    Profiling Caenorhabditis elegans non-coding RNA expression with a combined microarray

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    Small non-coding RNAs (ncRNAs) are encoded by genes that function at the RNA level, and several hundred ncRNAs have been identified in various organisms. Here we describe an analysis of the small non-coding transcriptome of Caenorhabditis elegans, microRNAs excepted. As a substantial fraction of the ncRNAs is located in introns of protein-coding genes in C.elegans, we also analysed the relationship between ncRNA and host gene expression. To this end, we designed a combined microarray, which included probes against ncRNA as well as host gene mRNA transcripts. The microarray revealed pronounced differences in expression profiles, even among ncRNAs with housekeeping functions (e.g. snRNAs and snoRNAs), indicating distinct developmental regulation and stage-specific functions of a number of novel transcripts. Analysis of ncRNA–host mRNA relations showed that the expression of intronic ncRNA loci with conserved upstream motifs was not correlated to (and much higher than) expression levels of their host genes. Even promoter-less intronic ncRNA loci, though showing a clear correlation to host gene expression, appeared to have a surprising amount of ‘expressional freedom’, depending on host gene function. Taken together, our microarray analysis presents a more complete and detailed picture of a non-coding transcriptome than hitherto has been presented for any other multicellular organism
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